AI-Native · 21 CFR Part 11 Compliant

AccuraTrials

The AI-native EDC that builds, validates, monitors, and audits your trial for you. From protocol PDF to clean clinical data — without a single programmer.From protocol to clean clinical data — without a programmer. The AI-native EDC that builds, validates, monitors, and audits your trial for you.

Four AI systems work together: Build reads your protocol and drafts complete eCRFs. Validate turns plain-English rules into tested edit checks. Monitor watches every data point for anomalies, deviations, and missing values. Audit reviews millions of trail entries so you see risk before an inspector does. 21 CFR Part 11 compliant. Same-day amendments. No vendor change orders. Four AI systems: Build drafts eCRFs from your protocol. Validate turns plain English into edit checks. Monitor watches every data point. Audit reviews trail activity for risk. 21 CFR Part 11 compliant. No vendor change orders.

21 CFR Part 11·ICH E6(R2) GCP·HIPAA Compliant·GDPR Compliant·Immutable Audit Trail·E-Signature Credential Re-Auth·ODM XML Export·Automated Part 11 Test Suite·Data Lock Workflow·Source Data Verification·21 CFR Part 11·ICH E6(R2) GCP·HIPAA Compliant·GDPR Compliant·Immutable Audit Trail·E-Signature Credential Re-Auth·ODM XML Export·Automated Part 11 Test Suite·Data Lock Workflow·Source Data Verification·

Your current EDC is the most expensive tool you own.

These are documented industry figures. AccuraTrials was purpose-built to attack every one of these cost drivers.AccuraTrials was purpose-built to attack these cost drivers.

$141K–$535K
per protocol amendment (Phase II–III)

Legacy EDC: every protocol change means reprogramming, re-validation, retraining. Phase II amendments cost $141K median; Phase III costs $535K median. With AccuraTrials, you update forms and rules yourself — same day, no change order, no vendor ticket.

Phase I: ~$75KPhase II: $141KPhase III: $535K
$500K–$800K/day
lost per day of trial delay (in foregone sales)

Every day your study isn't live is lost market exclusivity. Oncology: $840K/day median. Cardiovascular: $1.4M/day. AccuraTrials compresses the build cycle: AI drafts your eCRFs, you refine them, and your team goes live radically faster.

Oncology: $840K/dayCardio: $1.4M/dayRare Disease: $200K/day
76%
of protocols require amendments (avg 3.3 each)

Protocols change. 76% require at least one amendment, averaging 3.3 per study. Implementation takes 260 days average. In a legacy EDC, each one restarts the cost clock. AccuraTrials deploys amendments same-day, no vendor involved.

260 days to implement3.3 amendments avg215 days site lag

Describe your rule in English.
The AI writes the edit check.

"Age must be 18 or older." "Onset date can't be before consent." Type what you need. The AI writes the edit check — field, operator, value, outcome. Review it. Click Apply. Done."Age must be 18+." Type it. The AI writes the edit check. Review. Apply. Done.

2–4 weeksLegacy: Programmer writes, tests, validates each rule
30 secondsAccuraTrials: Describe in English, AI suggests, you apply
  • Plain English → edit check logic — AI proposes field, operator, value, and outcome in one step
  • 4 outcomes — Block Save, Auto-Query, Warning, or Conditional Required — per rule
  • Live preview — See the rule fire in real-time as you build it
  • No programmer, no vendor ticket, no change order — Amendments deploy the same day
See AI Validation →

Drop in a protocol.
Get your study back.

No more weeks of manual spec writing. Upload a protocol PDF — the AI reads it and drafts your visits, forms, fields, branching logic, and data dictionary. You refine it with a visual editor. That's it.Upload a protocol PDF. The AI drafts your visits, forms, fields, and branching logic. You refine it. That's it.

  • Full eCRF draft — Visits, forms, 78 field types, data dictionary — not a blank canvas
  • Branching logic included — Skip logic, form links, and conditional display, suggested from protocol text
  • You stay in control — Review, tweak, and approve everything in a visual editor before go-live
See AI Protocol Parser →

An AI that watches
every data point you enter.

Standard validation catches what you code for. The AI Copilot catches what you didn't think to code — missing data, out-of-window visits, impossible vitals combinations, and protocol deviations — flagging them for human review before they compound into inspection findings.The AI Copilot catches what standard validation misses — flagging anomalies, missing data, and protocol deviations for human review before they compound.

  • Catches the impossible — 4'10", 400 lbs? Flagged. Onset before consent? Flagged. All for your review.
  • Built-in chatbox — Sites ask questions, get protocol clarifications, and resolve queries without leaving the form.
  • Auto-drafts queries — Flagged anomalies get discrepancy notes drafted and routed to SDV, ready for monitor review.
See AI Copilot →

The FDA demands transparency.
We record everything.

Using AI in clinical trials requires trust. Every AI suggestion, prompt, and user decision is logged in the immutable audit trail — what was suggested, what was accepted, what was modified, and by whom. Human-in-the-loop is enforced. Everything is inspection-ready.Every AI suggestion, acceptance, and modification is logged in the immutable audit trail. Human-in-the-loop is enforced. Everything is inspection-ready.

21 CFR Part 11

E-signature credential re-auth · Immutable audit trail · Automated Part 11 test harness runs on every build

AI Audit Trail

The AI's logic, prompts, and suggestions are logged permanently. If the AI suggests a rule, the audit trail proves a human approved it.

ICH E6(R2) GCP

Full subject lifecycle traceability · SDV workflow · Protocol amendment audit capture

Session Control

Idle timeout (10 min warning / 20 min logout) · Device fingerprinting · 28 granular permissions

HIPAA

PHI field designation per eCRF · Role-scoped access to subject data · Full access audit trail

GDPR

Configurable retention policies · Data access audit · Per-site user access controls

"Every data modification—whether by a site user, a monitor, or the AI Copilot—is logged with timestamp, user, reason, and prior value. Records cannot be altered after write."

"
AccuraTrials brought enterprise EDC capabilities within reach for our organization. The compliance features, ease of use, and no-code configuration were critical for our research operations at Phoenix-Aid.
AK
Ashwinraj Karthikeyan
CEO, Phoenix-Aid · Early Adopter & Advisor

Built in Wisconsin.
Validated by the industry.

Origin

Built in Madison, Wisconsin

AccuraTrials was founded to solve a problem its team lived firsthand: clinical trials shouldn't require a dedicated programmer just to build a study.

Pitch Event

Gener8tor Showcase

Featured at the Madison startup ecosystem's premier pitch event, presenting AccuraTrials' vision for eliminating the programmer dependency in clinical EDC systems.

Standards

Built on Open Standards

AccuraTrials uses CDISC-aligned data models, CDASH field libraries, ODM XML export, and FHIR-ready EHR integration — ensuring interoperability with the clinical research ecosystem.

21 CFR Part 11
ICH E6(R2) GCP
HIPAA Compliant
GDPR Compliant
CDISC / ODM XML

Common questions,
direct answers.

If you don't find what you need, email jgui@accuratrials.com directly.

Request a Demo →
Yes. Every electronic signature requires credential re-authentication. Every data change writes to an immutable, tamper-evident audit trail with timestamp, user, prior value, new value, and reason. An automated Part 11 compliance test suite runs on every build.
Simple studies can be production-ready in days using the 8-tab study wizard. No EDC programmer required. Form templates, visit schedules, and site assignments can all be configured in the same session.
No. The Form Builder, Validation Rule Builder, and Branching Logic editor are all no-code interfaces. The AI Rule Suggester lets you describe a constraint in plain English — it proposes the edit check logic automatically.
Form templates can be updated and versioned mid-study without external programming resources. Branching logic and validation rules can be modified directly. All changes are audit-logged with their effective date.
PDF, Microsoft Excel, CSV, ODM XML (CDISC standard), and tab-delimited. A dedicated /regulatory-export endpoint is available for submission packages. All exports include the complete audit trail.
Yes. Sites are managed independently with per-site staff assignments, role-based access controls, and site-level enrollment reporting. Queries, SDV workflows, and user permissions are all scoped to individual sites.
AccuraTrials supports stratified randomization with configurable stratification factors, sealed allocation lists, and an emergency unblinding workflow with credential re-authentication and audit capture. RTSM/IRT kit and shipment tracking is integrated.
AccuraTrials includes a Capacitor-based Android build path for mobile data capture and a wound imaging module for photo-documented clinical assessments.

Your next study doesn't need
an EDC programmer.

30-minute demo. We'll show you all four AI systems working on your exact study type — Build, Validate, Monitor, Audit. Bring your hardest protocol. No commitment.30-minute demo. Bring your hardest protocol. See all four AI systems in action.

✓ No commitment required✓ Technical questions welcome✓ Response within 24 hours